The resveratrol

An anti-aging

The injectable resveratrol

Found in certain fruits such as grapes, blackberries or peanuts, the resveratrol is a polyphenol beneficial for:

  • Skin protection and the battle against wrinkles,
  • Extension of the lifespan,
  • Antioxidant action,
  • Anti-inflammatory activities,
  • Anti-tumor properties,
  • Cardioprotective effects,
  • Lowering bad cholesterol,
  • Control of type 2 diabetes.

Skin protection and the battle against wrinkles

The main factor in the aging of the skin in contact with light, therefore the UV radiation, is the cutaneous oxidative stress (see free radicals in § antioxidant).
The resveratrol has a photoprotective effect which greatly reduces the production of free radicals, thus protects the skin from aging.
An effective protection against UVA rays is observed with the resveratrol by the action of concentration in the nucleus of the Nrf2 protein.
Since 2003 the protective effects of resveratrol have also been demonstrated on UVB rays. Clinical studies now show the anti-wrinkle effect on deep wrinkles, which can quickly be reduces up to 24% lower.

Extension of the lifespan

In 2003, Howitz and his collaborators demonstrated that the resveratrol used on certain cells offered a 70% longer lifespan, going from 21 generations on average to 35.7.
Studies in vertebrates have shown an increase in the median lifespan, the maximum age while improving motor activity.
Current studies show that resveratrol increases lifespan in obese people by counteracting the harmful effects of a high fat diet.
Studies in mice show that in the context of a rich diet, weight gain is 40% less important with subjects treated with resveratrol.
Clinical studies have also shown the beneficial effect of resveratrol on glucose opening up the perspectives for people with type 2 diabetes.

Antioxidant action

The lipids disintegrated by oxidative stress cause the formation of free radicals.
Oxidized lipids are deposited in the blood vessels causing the atheromatous plaques that disrupt the functioning of cell membranes.
Resveratrol greatly reduces this oxidative stress.

Anti-inflammatory activities

When the arterial wall is damaged, platelets tend to aggregate and adhere on to the damaged walls, causing vasoconstriction.
The resveratrol inhibits this phenomenon, making it a powerful cardioprotector.
As we know, since 2010, that resveratrol decreases a microRNA (miR-155) responsible for the inflammatory reaction.

Anti-tumor properties

The resveratrol is a promising agent in chemoprevention.

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